conclusions: these results indicate preventive effects of all natural adjuvants (especially g2) on pathological changes of the lung in sensitized guinea pigs. results: all pathological changes in s group including the eosinophil infiltration (scoring 3.28 ± 0.28), lymphocyte infiltration (2.82 ± 0.26), local epithelial necrosis (2.71 ± 0.47) and mucosal plug (2.75 ± 0.37) were significantly hig...

background & objectives: respiratory, central nervous system, and skin complications of mustard gas toxicity have previously been studied; however, the liver and kidney side effects due to this intoxication have not been fully noted. we aimed to evaluate the frequency of liver, kidney and lung lesions in mustard gas-exposed iranian veterans who had been exposed to the toxin almost 2 decades...

objective(s):bone marrow-derived mesenchymal stem cells (bmscs) have attracted significant interest to treat asthma and its complication. in this study, the effects of bmscs on lung pathology and inflammation in an ovalbumin-induced asthma model in mouse were examined. materials and methods:balb/c mice were divided into three groups: control group (animals were not sensitized), asthma group (an...

background: lung cancer is one of the most fatal and preventable cancers. in this study, we sought to investigate about trend in incidence of lung cancer in kermanshah province -iran. methods: all pathology reports on lung cancer were collected from pathology centers in kermanshah province in recent 11 years (1997-2007). after merging the data with cases reported in, province health centre data...

Aims: Mustard gas is an alkalizing substance that can lead to damage to DNA and intracellular enzymes. The aim of this study was to investigate the expression of CXCL10 in chemically-injured veterans’ lung tissue.  Materials & Methods: This case-control study was done on 16 lung paraffin blocks of individuals exposed to mustard gas and 7 lungs paraffin blocks not-exposed people as...

Microscopic examination of stained smears and tissue sections remains the standard method for definitive diagnosis and classification of lung cancer. However, the morphology of lung cancer is complex, and consensus classifications such as those prepared by a panel World Health Organization (WHO) are required for the sake of consistency and clinical relevance. In the most recent (1999) WHO class...